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Bis(1-Methylethyl)Phenylphosphine CAS NO 6372-43-6


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CAS No.:6372-43-6

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

Bis(1-Methylethyl)Phenylphosphine is a versatile organophosphorus compound, specifically a tertiary phosphine ligand, valued for its electron-donating properties and steric bulk. Its primary commercial importance lies in its role as a crucial ligand in homogeneous catalysis, particularly in cross-coupling and hydrogenation reactions. This chemical is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity intermediates for complex synthesis.

Application

  • Homogeneous Catalysis: Acts as a key ligand for transition metal catalysts (e.g., palladium, rhodium) in cross-coupling reactions like Suzuki, Heck, and Sonogashira couplings.
  • Pharmaceutical Intermediates: Used in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs) where precise stereochemical control is required.
  • Agrochemical Synthesis: Employed in the production of advanced pesticides and herbicides that utilize organophosphorus chemistry.
  • Polymer Chemistry: Serves as a catalyst component or chain-transfer agent in the production of specialty polymers and materials.
  • Material Science Research: Utilized in the development of novel metal-organic frameworks (MOFs), nanomaterials, and electronic materials.
  • Organic Synthesis: Functions as a nucleophilic catalyst or reducing agent in various organic transformations.

Basic Information

Product Name Bis(1-Methylethyl)Phenylphosphine
CAS No. 6372-43-6
Molecular Formula C12H19P
Molecular Weight 194.25 g/mol
Synonyms Diisopropylphenylphosphine; Phenylbis(1-methylethyl)phosphine; Phenyl-di-iso-propylphosphine; Diisopropyl(phenyl)phosphine; (Phenyl)diisopropylphosphine; P,P-Diisopropylphenylphosphine; 1-Methylethyl(phenyl)phosphine (alternate); Phosphine, phenylbis(1-methylethyl)-
EINECS 228-923-3

Quality Control

Our Bis(1-Methylethyl)Phenylphosphine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, NMR, and titration methods, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Due to its sensitivity to oxidation, containers must be kept sealed and purged after each use to maintain product integrity.

Specification

Item Specification
Appearance Colorless to pale yellow liquid
Identification (IR) Conforms to structure
Assay (GC) ≥ 97.0%
Water Content (KF) ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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