Description

Ac-Tyr-Nhme CAS NO 6367-14-2 is a protected tyrosine derivative, specifically N-Acetyl-L-tyrosine methyl ester, widely used as a key synthetic intermediate in peptide chemistry. This compound is critical for researchers and manufacturers requiring high-purity building blocks to ensure the integrity and yield of complex peptide sequences. It is essential for pharmaceutical R&D, proteomics studies, and the production of bioactive peptides and APIs.

Application

• Peptide Synthesis: Serves as a crucial protected amino acid building block in solid-phase and solution-phase peptide synthesis (SPPS).
• Pharmaceutical Intermediates: Used in the research and development of novel therapeutic peptides and active pharmaceutical ingredients (APIs).
• Biochemical Research: Employed as a substrate or standard in enzymatic studies and proteomics research.
• Chemical Biology: Acts as a precursor for labeling or modifying peptides for diagnostic and imaging applications.
• Academic & Industrial R&D: A fundamental reagent for exploring peptide structure-activity relationships (SAR) and new synthetic methodologies.

Basic Information

Product Name	Ac-Tyr-Nhme
CAS No.	6367-14-2
Molecular Formula	C₁₂H₁₅NO₄
Molecular Weight	237.25 g/mol
Synonyms	N-Acetyl-L-tyrosine methyl ester; Ac-L-Tyr-OMe; N-Acetyltyrosine methyl ester; L-Tyrosine, N-acetyl-, methyl ester; Methyl N-acetyl-L-tyrosinate; Acetyltyrosine methyl ester; (2S)-2-Acetamido-3-(4-hydroxyphenyl)propanoic acid methyl ester; Ac-Tyr-OMe
EINECS	228-886-8

Quality Control

Our Ac-Tyr-Nhme is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for sensitive synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Optical Rotation	[α]²⁰D: -20.0° to -24.0° (c=1 in methanol)
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm
Residue on Ignition	≤0.2%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.