Description

5-Bromosalicylamide is a halogenated salicylamide derivative, a versatile organic intermediate prized for its reactive bromine atom and phenolic amide functionality. This compound is critical for synthesizing more complex molecules in pharmaceutical and agrochemical research, where structural modification is key to developing new active ingredients. It serves as a valuable building block for medicinal chemists and process development scientists in the fine chemical and life science industries.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting anti-inflammatory or antimicrobial pathways.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides and herbicides, leveraging its halogenated aromatic structure.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic substitution reactions to introduce the salicylamide moiety.
• Chemical Research & Development: Serves as a standard or starting material in academic and industrial labs for method development and exploring new chemical entities.
• Material Science Precursor: Potential use in the synthesis of specialized polymers or ligands for metal-organic frameworks (MOFs).

Basic Information

Product Name	5-Bromosalicylamide
CAS No.	6329-74-4
Molecular Formula	C7H6BrNO2
Molecular Weight	216.03 g/mol
Synonyms	5-Bromo-2-hydroxybenzamide; 2-Hydroxy-5-bromobenzamide; Salicylamide, 5-bromo-; NSC 403697; 5-Bromosalicylamide; 5-Bromo-2-hydroxybenzoic acid amide
EINECS	228-690-7

Quality Control

Our 5-Bromosalicylamide is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, ensuring full traceability and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	193 - 197 °C
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.