Description

n-Chloroacetylglycine is a versatile organic building block and key intermediate in fine chemical synthesis. Its reactive chloroacetyl and glycine moieties make it a valuable precursor for the production of more complex molecules, particularly in pharmaceutical and agrochemical research. This compound is essential for manufacturers and R&D teams developing active pharmaceutical ingredients (APIs), peptide mimetics, and specialized chemical reagents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of various active pharmaceutical ingredients (APIs) and drug candidates.
• Peptide Chemistry: Used as a reagent for introducing the chloroacetyl group in peptide synthesis and for creating peptide conjugates.
• Agrochemical Synthesis: Serves as an intermediate in the production of certain herbicides, fungicides, and plant growth regulators.
• Bioconjugation & Linker Chemistry: Employed in the development of chemical linkers for antibody-drug conjugates (ADCs) and other bioconjugation strategies.
• Organic Synthesis Reagent: A useful starting material for heterocyclic chemistry and the preparation of N-acyl glycine derivatives.
• Research & Development: Critical compound in medicinal chemistry and biochemical research for exploring new synthetic pathways.

Basic Information

Product Name	n-Chloroacetylglycine
CAS No.	6319-96-6
Molecular Formula	C4H6ClNO3
Molecular Weight	151.55 g/mol
Synonyms	Chloroacetylglycine; N-(Chloroacetyl)glycine; 2-[(Chloroacetyl)amino]acetic acid; Glycine, N-chloroacetyl-; Chloroacetamidoacetic acid; Acetic acid, (chloroacetylamino)-; NSC 401564
EINECS	228-656-5

Quality Control

Our n-Chloroacetylglycine is manufactured under a strict quality management system to ensure batch-to-batch consistency and high purity. We provide comprehensive quality documentation, including detailed Certificates of Analysis (COA) for each lot, which specify purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated research and development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	118 - 122 °C
Loss on Drying	≤ 1.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.