Description

2-[(2-Fluoroacetyl)Amino]-3-Phenyl-Propanoic Acid is a specialized fluorinated amino acid derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both a phenylalanine backbone and a fluoroacetyl group, makes it a valuable intermediate for constructing complex molecules with targeted biological activity. This compound is primarily utilized by research institutions and pharmaceutical developers engaged in the creation of novel peptide-based therapeutics, enzyme inhibitors, and diagnostic agents.

Application

• Pharmaceutical Intermediate: Key synthon for the development of protease inhibitors and other bioactive peptides.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to introduce fluorine atoms, modulating metabolic stability and binding affinity.
• Bioconjugation: Serves as a linker or modifying agent for labeling proteins and antibodies in diagnostic probe development.
• Chemical Biology Tool: Employed in the synthesis of activity-based probes (ABPs) for studying enzyme function and mechanism.
• Agrochemical Research: Potential intermediate in the design of novel herbicides or plant growth regulators with enhanced properties.
• Academic Synthesis: A valuable compound for teaching and research in advanced organic and fluorine chemistry.

Basic Information

Product Name	2-[(2-Fluoroacetyl)Amino]-3-Phenyl-Propanoic Acid
CAS No.	6310-38-9
Molecular Formula	C11H12FNO3
Molecular Weight	225.22 g/mol
Synonyms	N-(2-Fluoroacetyl)-L-phenylalanine; 2-[(2-Fluoroacetyl)amino]-3-phenylpropanoic acid; (S)-2-(2-Fluoroacetamido)-3-phenylpropanoic acid; L-Phenylalanine, N-(2-fluoroacetyl)-; 2-Fluoroacetamido-3-phenylpropionic acid; N-Fluoroacetylglycine, 3-phenyl-; Fluoroacetylphenylalanine; FA-Phe-OH
EINECS	Contact for details

Quality Control

Our 2-[(2-Fluoroacetyl)Amino]-3-Phenyl-Propanoic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis for enantiomeric excess, and spectroscopic identification (NMR, IR, MS). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or development specifications. Custom purity grades, including research and pharmaceutical intermediate standards, are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.