Description

Potassium Difluoroacetate is a versatile organofluorine building block and reagent. This compound is valued for its ability to introduce the difluoroacetate moiety, a key functional group in the synthesis of complex molecules. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors for applications ranging from medicinal chemistry to polymer modification.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing active pharmaceutical ingredients (APIs), particularly those containing difluoromethyl or difluoroacetate groups to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the research and production of modern pesticides and herbicides, where the introduction of fluorine atoms can enhance biological activity and environmental persistence.
• Organic Synthesis Reagent: Serves as a source of the difluoroacetate anion in nucleophilic substitution and esterification reactions for constructing complex organic molecules in R&D laboratories.
• Material Science Research: Employed in the development of specialty polymers, coatings, and electronic materials where fluorinated compounds impart desirable properties like chemical resistance or low surface energy.
• Ligand and Catalyst Preparation: Useful in the synthesis of fluorinated ligands for metal complexes used in catalysis and material science applications.

Basic Information

Product Name	Potassium Difluoroacetate
CAS No.	6291-26-5
Molecular Formula	C2HF2KO2
Molecular Weight	134.12 g/mol
Synonyms	Difluoroacetic Acid Potassium Salt; Potassium 2,2-Difluoroacetate; 2,2-Difluoroacetic Acid Potassium Salt; KDFA; Acetic Acid, 2,2-Difluoro-, Potassium Salt; Potassium α,α-Difluoroacetate
EINECS	228-535-7

Quality Control

Our Potassium Difluoroacetate is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including assay (by titration or HPLC), identification (IR, NMR), and impurity profiling to ensure consistency and purity. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP and ISO 9001 standards for reliable supply to regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to prevent degradation. Keep away from incompatible materials such as strong acids and strong oxidizers.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (Titration)	≥ 98.0 %
Water Content (KF)	≤ 1.0 %
Heavy Metals (as Pb)	≤ 20 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.