Description

1-Propynyldiphenylphosphine is a specialized organophosphorus compound featuring a propynyl group attached to a diphenylphosphine moiety. This structure makes it a valuable ligand and building block in advanced synthetic chemistry, particularly for catalyzing and directing complex organic transformations. It is essential for researchers and process chemists in the pharmaceutical, agrochemical, and materials science industries who require precise control over metal-catalyzed reactions.

Application

1-Propynyldiphenylphosphine serves as a versatile reagent and ligand in sophisticated chemical synthesis. Key applications include:

• Transition Metal Catalysis: As a ligand for palladium, nickel, and other transition metals in cross-coupling reactions (e.g., Sonogashira, Suzuki-Miyaura).
• Pharmaceutical Intermediate Synthesis: Building block for creating complex molecular architectures in active pharmaceutical ingredient (API) development.
• Agrochemical Research: Used in the synthesis of novel compounds for crop protection and pest management.
• Materials Science: Precursor for the development of specialized polymers, ligands for metal-organic frameworks (MOFs), and advanced functional materials.
• Academic & Industrial R&D: A critical tool for methodological development in organic and organometallic chemistry laboratories.

Basic Information

Product Name	1-Propynyldiphenylphosphine
CAS No.	6224-94-8
Molecular Formula	C15H13P
Molecular Weight	224.24 g/mol
Synonyms	Diphenyl(prop-1-yn-1-yl)phosphine; (Prop-1-yn-1-yl)diphenylphosphane; Diphenyl(1-propynyl)phosphine; Prop-1-yn-1-yldiphenylphosphine; 1-Propynyl-diphenyl-phosphine; Propargyl-diphenyl-phosphine (ambiguous); P,P-Diphenyl-P-propynylphosphine
EINECS	Contact for details

Quality Control

Our 1-Propynyldiphenylphosphine is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including NMR, HPLC, and GC analysis, to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee it meets your research and production requirements.

Storage

Preserve in a tightly closed container, protected from light. Due to its sensitivity to oxidation, this material should be stored under an inert atmosphere (argon or nitrogen) in a cool, dry place. Recommended long-term storage temperature is 2-8°C. Allow the container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 95% (Typical 97-99%)
1H NMR	Conforms
31P NMR	Conforms

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.