Description

Scopolamine n-Oxide Hydrobromide is a quaternary ammonium salt derivative of the tropane alkaloid scopolamine. This compound is of significant interest in advanced pharmaceutical research and development, particularly as a key intermediate or reference standard. It is primarily utilized by research institutions and pharmaceutical companies engaged in neuropharmacology, analytical method development, and the synthesis of novel therapeutic agents targeting the cholinergic system.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of more complex scopolamine derivatives and related active pharmaceutical ingredients (APIs).
• Analytical Reference Standard: Used for method development, validation, and quality control (QC) testing in HPLC, LC-MS, and other chromatographic assays.
• Neuropharmacological Research: Employed in preclinical studies to investigate muscarinic acetylcholine receptor (mAChR) interactions and the metabolic pathways of tropane alkaloids.
• Chemical Synthesis: Serves as a building block in organic synthesis for creating novel compounds with potential therapeutic applications.
• Metabolite Studies: Used as an analytical standard for the identification and quantification of scopolamine metabolites in biological matrices.

Basic Information

Product Name	Scopolamine n-Oxide Hydrobromide
CAS No.	6106-81-6
Molecular Formula	C17H22BrNO5
Molecular Weight	400.27 g/mol
Synonyms	Scopolamine N-Oxide HBr; Scopolamine N-Oxide Hydrobromide Salt; 6β,7β-Epoxy-3α-hydroxy-8-methyl-1αH,5αH-tropanium-1α-yl (-)-tropate N-Oxide Hydrobromide; Hyoscine N-Oxide Hydrobromide; Scopolammonium Bromide N-Oxide; Tropate, 6,7-epoxytropan-3α-yl ester, N-oxide, hydrobromide; 6106-81-6
EINECS	Contact for details

Quality Control

Our Scopolamine n-Oxide Hydrobromide is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets the stringent requirements for research and development use. Certificates of Analysis (COA) detailing all test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.