Description

6-Phthalimido-1-Hexyne is a specialized alkyne derivative featuring a phthalimide protecting group. This compound is a valuable synthetic intermediate in organic chemistry, prized for its role in constructing complex molecular architectures via click chemistry and other alkyne-based transformations. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and advanced materials.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, particularly those requiring alkyne functionalization for further coupling reactions.
• Agrochemical Research: Used in the development of new pesticides and herbicides where the alkyne moiety enables modular synthesis of diverse compound libraries.
• Material Science: Serves as a monomer or cross-linking agent in the preparation of specialized polymers and dendrimers with tailored properties.
• Bioconjugation: Employed in click chemistry (e.g., CuAAC reactions) for labeling biomolecules such as proteins, peptides, and nucleic acids in diagnostic and biochemical research.
• Academic & Industrial R&D: A versatile reagent for methodological development in organic synthesis and catalysis studies.

Basic Information

Product Name	6-Phthalimido-1-Hexyne
CAS No.	6097-08-1
Molecular Formula	C₁₄H₁₃NO₂
Molecular Weight	227.26 g/mol
Synonyms	N-(5-Hexynyl)phthalimide; 1-Phthalimido-5-hexyne; 5-(Phthalimido)-1-pentyne; 6-Phthalimid-1-hexin; Phthalimidohex-1-yne; N-(5-Hexyn-1-yl)phthalimide
EINECS	Contact for details

Quality Control

Our 6-Phthalimido-1-Hexyne is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and FTIR, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee compliance with your research and development requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept sealed and stored away from direct light and moisture to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.