Description

2-Bromo-2,3,3,3-Tetrafluoropropanoyl Chloride is a highly reactive fluorinated building block essential for advanced organic synthesis. Its core value lies in introducing both bromine and a highly electrophilic acid chloride group into a perfluorinated carbon chain, enabling precise molecular construction. This compound is critically needed by R&D chemists and process engineers in the pharmaceutical, agrochemical, and specialty materials industries for developing novel active ingredients and high-performance polymers.

Application

• Pharmaceutical Intermediate: A key precursor for synthesizing fluorinated active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the production of advanced, high-efficacy herbicides and pesticides where the fluorine atoms enhance bioavailability and environmental stability.
• Liquid Crystal & OLED Materials: Serves as a critical building block for fluorine-containing liquid crystals and organic light-emitting diode (OLED) materials, improving electronic properties and device longevity.
• Polymer Modification: Employed to introduce fluorinated side chains into polymers, enhancing their chemical resistance, thermal stability, and surface properties for coatings and engineering plastics.
• Organic Synthesis Reagent: Acts as a versatile reagent for Friedel-Crafts acylation and other coupling reactions to create complex, fluorinated aromatic and heterocyclic compounds.
• Surface Active Agent Precursor: Used in the synthesis of fluorinated surfactants and surface treatment agents for textiles, electronics, and fire-fighting foams.

Basic Information

Product Name	2-Bromo-2,3,3,3-Tetrafluoropropanoyl Chloride
CAS No.	6066-45-1
Molecular Formula	C3BrClF4O
Molecular Weight	243.38 g/mol
Synonyms	2-Bromo-2,3,3,3-tetrafluoropropanoyl chloride; 2-Bromo-2,3,3,3-tetrafluoropropionic acid chloride; Perfluorobromopropionyl chloride; α-Bromo-α,β,β,β-tetrafluoropropionyl chloride; 2-Bromo-3,3,3-trifluoro-2-(trifluoromethyl)propanoyl chloride (incorrect but common misnomer); Bromotetrafluoropropionyl chloride; Propanoyl chloride, 2-bromo-2,3,3,3-tetrafluoro-
EINECS	Contact for details

Quality Control

Our 2-Bromo-2,3,3,3-Tetrafluoropropanoyl Chloride is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including GC, NMR, and titration, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, assay, and impurity profiles are provided with each shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) when not in use. Keep away from strong bases, oxidizers, and sources of ignition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Impurities (GC)	≤ 2.0% total

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.