Description

Ethylmalonyl-Coenzyme A is a crucial biochemical intermediate in the biosynthesis of polyketide natural products. This compound matters as a high-purity, research-grade reagent essential for studying and manipulating metabolic pathways in microorganisms and plants. It is primarily needed by researchers and manufacturers in the pharmaceutical, biotechnology, and agricultural sectors for enzyme mechanism studies, pathway engineering, and the development of novel bioactive compounds.

Application

• Biochemical Research: Critical substrate for in vitro studies of polyketide synthases (PKS) and related enzymes.
• Metabolic Pathway Analysis: Used to trace and understand the biosynthesis of complex natural products like antibiotics and statins.
• Enzyme Kinetics & Inhibition Studies: Serves as a standard for assaying enzyme activity and screening for potential inhibitors.
• Synthetic Biology: A key building block for engineering microbial cell factories to produce high-value polyketides.
• Pharmaceutical Development: Supports R&D for novel therapeutics derived from polyketide scaffolds.
• Academic Research: Fundamental tool in university and institutional labs focusing on chemical biology and natural product chemistry.

Basic Information

Product Name	Ethylmalonyl-Coenzyme A
CAS No.	6049-57-6
Molecular Formula	C₂₆H₄₂N₇O₁₉P₃S
Molecular Weight	897.63 g/mol
Synonyms	Ethylmalonyl-CoA; (2R)-2-Ethyl-3-oxopropanoyl-CoA; 2-Ethyl-3-oxopropanoyl coenzyme A; Coenzyme A, S-(2-ethyl-3-oxopropanoate); Ethylmalonyl coenzyme A; EM-CoA; 2-Ethylmalonyl-Coenzyme A
EINECS	Contact for details

Quality Control

Our Ethylmalonyl-Coenzyme A is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot undergoes comprehensive analytical testing including HPLC for purity and identity confirmation. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive) and light-sensitive; handle under inert atmosphere or in a controlled, dry environment when possible to ensure long-term stability.

Specification

Item	Specification
Appearance	White to off-white powder or lyophilized solid
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0 %
Biological Activity	Functional in standard enzyme assay

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.