Description

H-D-Dap-Oh Hcl is a protected derivative of the non-proteinogenic amino acid 2,3-diaminopropionic acid (Dap), widely utilized as a critical building block in peptide synthesis. This compound matters for its role in introducing specific structural and functional elements into synthetic peptides, enabling advanced research and development. It is primarily needed by pharmaceutical researchers, biotech companies, and fine chemical manufacturers engaged in the development of novel peptide-based therapeutics, diagnostic agents, and biochemical tools.

Application

• Peptide Synthesis: A key intermediate for the solid-phase and solution-phase synthesis of complex peptides, particularly those requiring a diaminopropionic acid backbone.
• Pharmaceutical Research: Used in the development and structure-activity relationship (SAR) studies of peptide drugs, including antimicrobial peptides and hormone analogs.
• Bioconjugation: Serves as a linker or spacer molecule for attaching functional groups, labels, or other molecules to peptides or proteins.
• Chemical Biology: Employed in the synthesis of peptide mimetics and probes to study biological pathways and protein-protein interactions.
• Agrochemical Development: Potential use in the synthesis of bioactive peptide derivatives for crop protection.

Basic Information

Product Name	H-D-Dap-Oh Hcl
CAS No.	6018-55-9
Molecular Formula	C3H9N2O2•HCl
Molecular Weight	156.58 g/mol
Synonyms	H-D-Dap-OH hydrochloride; (R)-2,3-Diaminopropionic acid hydrochloride; D-2,3-Diaminopropanoic acid hydrochloride; D-Dap-OH•HCl; (2R)-2,3-Diaminopropanoic acid hydrochloride; Boc-D-Dap(Fmoc)-OH related intermediate; Fmoc-D-Dap(Boc)-OH precursor; D-α,β-Diaminopropionic acid HCl
EINECS	Contact for details

Quality Control

Our H-D-Dap-Oh Hcl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis, and identity confirmation, to ensure it meets the high standards required for peptide synthesis. Certificates of Analysis (COA) with detailed specifications are available for every shipment upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Optical Rotation	Contact for details
Chiral Purity (HPLC)	≥99.0%
Water Content (KF)	≤1.0%
Heavy Metals	≤10 ppm
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.