Description

1-Chloro-3,4-Difluorobenzene is a versatile halogenated aromatic building block of significant importance in advanced organic synthesis. Its value lies in the strategic positioning of chlorine and fluorine atoms on the benzene ring, which allows for selective functionalization and modulation of electronic properties in target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it serves as a key intermediate for creating active ingredients and specialty materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a difluorobenzene core.
• Agrochemical Synthesis: Used in the manufacturing of advanced herbicides, fungicides, and pesticides, where the halogenated ring contributes to biological activity and stability.
• Liquid Crystal & OLED Materials: Serves as a building block for fluorine-containing compounds used in electronic display technologies and organic light-emitting diodes.
• Polymer & Resin Modification: Employed to introduce fluorine and chlorine functionalities into polymer chains, enhancing properties like chemical resistance and thermal stability.
• Organic Synthesis Reagent: Acts as a starting material or reactant in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D labs exploring new fluorinated compounds and their properties.

Basic Information

Product Name	1-Chloro-3,4-Difluorobenzene
CAS No.	696-02-6
Molecular Formula	C6H3ClF2
Molecular Weight	148.54 g/mol
Synonyms	3,4-Difluorochlorobenzene; 3,4-Difluoro-1-chlorobenzene; 1-Chloro-3,4-difluorobenzol; 3,4-Difluorophenyl chloride; 696-02-6; NSC 92440; Benzene, 1-chloro-3,4-difluoro-
EINECS	211-792-4

Quality Control

Our 1-Chloro-3,4-Difluorobenzene is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids and organic solvents. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Related Substances (GC)	Total impurities ≤ 2.0%
Density (at 20°C)	~1.35 g/mL
Refractive Index (n20D)	~1.47

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.