Description

Ethyl-2,4,4,4-Tetrafluoroacetoacetate is a versatile fluorinated building block essential for introducing the tetrafluoroacetoacetate moiety into complex molecular architectures. This compound is critical for synthesizing advanced materials and active pharmaceutical ingredients (APIs) that require enhanced metabolic stability and lipophilicity. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of fluorinated heterocycles and active pharmaceutical ingredients (APIs) for improved drug efficacy and stability.
• Agrochemical Synthesis: Building block for developing novel fluorinated pesticides and herbicides with enhanced activity and environmental profile.
• Material Science: Used in the production of fluorinated polymers and advanced organic electronic materials.
• Chemical Research: A valuable reagent in academic and industrial R&D for exploring new fluorination methodologies and creating compound libraries.
• Ligand and Catalyst Development: Serves as a precursor for β-diketonate ligands used in coordination chemistry and catalysis.

Basic Information

Product Name	Ethyl-2,4,4,4-Tetrafluoroacetoacetate
CAS No.	685-69-8
Molecular Formula	C6H6F4O3
Molecular Weight	202.11 g/mol
Synonyms	Ethyl 4,4,4-Trifluoro-3-oxobutanoate; Ethyl 4,4,4-Trifluoroacetoacetate; 4,4,4-Trifluoro-3-oxobutanoic Acid Ethyl Ester; 2,4,4,4-Tetrafluoroacetoacetic Acid Ethyl Ester; Ethyl Tetrafluoroacetoacetate; 3-Oxo-4,4,4-trifluorobutanoic Acid Ethyl Ester; ETTFAA; TFAAE
EINECS	211-694-8

Quality Control

Our Ethyl-2,4,4,4-Tetrafluoroacetoacetate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, HPLC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong bases and incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.