Description

2-Bromoacetamide is a versatile brominated organic building block with significant utility in synthetic chemistry. Its reactive bromomethyl group adjacent to the amide functionality makes it a valuable reagent for alkylation and the synthesis of more complex heterocyclic and pharmaceutical intermediates. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce acetamide-based moieties into target molecules.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing nitrogen heterocycles or modified amino acid structures.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators that require halogenated acetamide motifs.
• Chemical Research & Development: Serves as a versatile alkylating agent in organic synthesis for introducing the -CH2Br group into nucleophiles under controlled conditions.
• Peptide Modification: Employed for the selective modification of peptides and proteins by reacting with cysteine residues or other nucleophilic amino acids.
• Polymer Chemistry: Can act as a monomer or cross-linking agent in the preparation of functional polymers and hydrogels.
• Ligand and Catalyst Preparation: Useful for synthesizing specialized ligands for metal complexes and catalysts used in asymmetric synthesis.

Basic Information

Item	Detail
Product Name	2-Bromoacetamide
CAS No.	683-57-8
Molecular Formula	C2H4BrNO
Molecular Weight	137.96 g/mol
Synonyms	Bromoacetamide; α-Bromoacetamide; 2-Bromoethanamide; Bromoacetic acid amide; Acetamide, 2-bromo-; NSC 7897; USAF EK-3945
EINECS	211-673-6

Quality Control

Our 2-Bromoacetamide is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	91 - 94 °C
Loss on Drying	≤ 1.0 %
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.