Description

Methyl Heptafluoroisobutyrate CAS NO 680-05-7 is a high-purity fluorinated ester, a key building block in advanced chemical synthesis. Its value lies in the unique properties imparted by the heptafluoroisobutyryl group, which introduces exceptional stability, lipophilicity, and resistance to metabolic degradation. This compound is essential for R&D and production teams in the pharmaceutical, agrochemical, and specialty materials sectors seeking to enhance product performance.

Application

• Pharmaceutical Intermediate: A critical precursor for synthesizing active pharmaceutical ingredients (APIs), particularly those requiring fluorinated moieties to improve bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the production of advanced herbicides, pesticides, and fungicides where the fluorine atoms enhance biological activity and environmental persistence.
• Polymer & Material Science: Serves as a monomer or modifier in the creation of fluorinated polymers, coatings, and surfactants that demand high chemical resistance, low surface energy, and thermal stability.
• Liquid Crystal & Electronic Chemicals: Employed in the synthesis of fluorinated liquid crystals and dielectric fluids for high-performance display and electronic applications.
• Organic Synthesis Reagent: Acts as a versatile reagent for introducing the heptafluoroisobutyrate group into complex molecules in research and fine chemical production.
• Surface Treatment & Coatings: Used in formulations for creating oil-, water-, and stain-repellent surfaces on textiles, paper, and other substrates.

Basic Information

Product Name	Methyl Heptafluoroisobutyrate
CAS No.	680-05-7
Molecular Formula	C5H3F7O2
Molecular Weight	228.07 g/mol
Synonyms	Methyl Perfluoroisobutyrate; Methyl 1,1,1,3,3,3-Hexafluoro-2-(trifluoromethyl)propionate; Methyl 2-(Trifluoromethyl)-3,3,3-trifluoropropionate; Heptafluoroisobutyric Acid Methyl Ester; Methyl α,α-Bis(trifluoromethyl)acetate; MFIBA; Perfluoroisobutyric Acid Methyl Ester
EINECS	211-667-8

Quality Control

Our Methyl Heptafluoroisobutyrate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including GC, NMR, and FTIR, to ensure identity, purity, and consistency. We provide Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding synthesis processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile nature, ensure containers are kept tightly sealed when not in use to prevent evaporation and concentration changes. Recommended storage temperature is 2-8°C for long-term stability, though short-term storage at controlled room temperature (15-25°C) is acceptable.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to reference spectrum
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Related Substances (GC)	Total impurities ≤ 2.0%
Density (at 20°C)	1.50 - 1.55 g/mL
Refractive Index (n20D)	1.300 - 1.310

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.