Description

(2,2,2-Trifluoroethoxy)Acetic Acid is a versatile fluorinated organic acid derivative. This compound is a valuable building block in advanced organic synthesis, prized for its ability to introduce trifluoroethoxy-containing motifs. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: Key building block for synthesizing active pharmaceutical ingredients (APIs), particularly those requiring trifluoroethoxy functional groups to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the fluorine moiety enhances biological activity and environmental persistence.
• Liquid Crystal & OLED Material Precursor: Serves as a starting material for creating fluorinated components in electronic display technologies and organic light-emitting diodes.
• Polymer Modification: Employed to introduce fluorine-containing side chains into polymers, altering their surface properties, chemical resistance, and thermal stability.
• Organic Synthesis Reagent: A useful reagent in academic and industrial R&D for constructing complex molecules, leveraging its carboxylic acid group for further derivatization.
• Specialty Chemical Manufacturing: Intermediate in the production of surfactants, lubricants, and other performance chemicals where fluorination is desired.

Basic Information

Product Name	(2,2,2-Trifluoroethoxy)Acetic Acid
CAS No.	675-67-2
Molecular Formula	C4H5F3O3
Molecular Weight	158.08 g/mol
Synonyms	2-(2,2,2-Trifluoroethoxy)acetic acid; Acetic acid, 2-(2,2,2-trifluoroethoxy)-; Trifluoroethoxyacetic acid; TFEAA; 2,2,2-Trifluoroethoxymethanoic acid; Glycolic acid, 2,2,2-trifluoroethyl ether; NSC 92440; 675-67-2
EINECS	211-625-7

Quality Control

Our (2,2,2-Trifluoroethoxy)Acetic Acid is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and titration, to ensure high purity and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.