Description

3-(Trifluoromethylthio)Benzonitrile is a versatile fluorinated aromatic building block characterized by the presence of both a nitrile and a trifluoromethylthio functional group. This unique structure makes it a valuable intermediate for synthesizing advanced molecules in pharmaceutical and agrochemical research. It is primarily sought after by R&D chemists and process development scientists working on novel active ingredients. The compound is supplied at a purity of 97%, ensuring reliable performance in demanding synthetic applications.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated motifs for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides where the trifluoromethylthio group can improve efficacy and environmental profile.
• Material Science Precursor: Serves as a building block for specialty polymers, liquid crystals, and organic electronic materials due to its aromatic core and functional handles.
• Chemical Research & Development: Employed in academic and industrial labs for exploring new reaction methodologies and creating compound libraries for screening.
• Ligand and Catalyst Design: The nitrile group can be transformed into various heterocycles or coordinating ligands used in catalytic systems.

Basic Information

Product Name	3-(Trifluoromethylthio)Benzonitrile
CAS No.	660-44-6
Molecular Formula	C8H4F3NS
Molecular Weight	203.18 g/mol
Synonyms	3-((Trifluoromethyl)thio)benzonitrile; m-(Trifluoromethylthio)benzonitrile; α,α,α-Trifluoro-m-tolyl thiocyanate; 3-Cyanophenyl trifluoromethyl sulfide; Benzonitrile, 3-[(trifluoromethyl)thio]-; 660-44-6; 3-Trifluoromethylsulfanyl-benzonitrile
EINECS	Contact for details

Quality Control

Our 3-(Trifluoromethylthio)Benzonitrile is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to verify identity, purity, and impurity profiles. Certificates of Analysis (COA) documenting these results are provided and available upon request to ensure full traceability and compliance with your internal quality standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.