Description

Tris(2,2,2-trifluoroethyl) borate is a specialized organoboron compound featuring three trifluoroethoxy groups attached to a central boron atom. This structure makes it a valuable reagent in advanced organic synthesis, particularly for introducing boron and fluorine-containing moieties. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries for applications such as cross-coupling reactions and the synthesis of complex fluorinated molecules.

Application

• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a boron source for the preparation of trifluoroethyl-substituted boronic esters or acids, key intermediates in creating complex aryl and heteroaryl compounds.
• Pharmaceutical Intermediate Synthesis: Used in the research and development of active pharmaceutical ingredients (APIs), especially those requiring fluorinated segments to modulate bioavailability and metabolic stability.
• Agrochemical Manufacturing: Employed in the synthesis of novel herbicides, fungicides, and insecticides where the trifluoroethyl group can enhance biological activity and environmental persistence.
• Advanced Materials Production: Acts as a precursor or modifying agent in the creation of specialty polymers, liquid crystals, and electronic materials that benefit from fluorine's unique properties.
• Organic Synthesis Reagent: Functions as a Lewis acid catalyst or a protecting group agent in various fluorination and functional group transformation processes.

Basic Information

Product Name	Tris(2,2,2-trifluoroethyl) Borate
CAS No.	659-18-7
Molecular Formula	C6H6BF9O3
Molecular Weight	271.91 g/mol
Synonyms	Boric Acid, Tris(2,2,2-trifluoroethyl) Ester; 2,2,2-Trifluoroethyl Borate; Tris(2,2,2-Trifluoroethoxy)borane; Boron, Tris(2,2,2-trifluoroethoxy)-; (2,2,2-Trifluoroethoxy)borane Oligomer; Trifluoroethyl Borate; B(OC2H2F3)3
EINECS	Contact for details

Quality Control

Our Tris(2,2,2-trifluoroethyl) borate is produced and handled under strict quality management protocols. Each batch undergoes comprehensive analytical testing to ensure high purity and consistency, meeting the stringent requirements for research and industrial synthesis. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms
Assay (GC or 11B NMR)	≥ 97.0%
Water Content (Karl Fischer)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.