Description

3-Fluorothioanisole is a versatile fluorinated aromatic sulfide building block of significant importance in advanced organic synthesis. Its unique structure, featuring both a fluorine atom and a thioether group, makes it a critical intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for applications such as medicinal chemistry, ligand synthesis, and the development of novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring fluorinated aromatic motifs to modulate bioavailability and metabolic stability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atom enhances biological activity and environmental persistence.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands in transition metal catalysis and organocatalysis, enabling novel synthetic transformations.
• Material Science Research: Employed in the development of organic electronic materials, such as semiconductors and liquid crystals, due to its electron-withdrawing and sulfur-containing properties.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the fine chemical market.

Basic Information

Product Name	3-Fluorothioanisole
CAS No.	658-28-6
Molecular Formula	C7H7FS
Molecular Weight	142.19 g/mol
Synonyms	1-Fluoro-3-(methylthio)benzene; 3-Fluoro-1-(methylthio)benzene; 3-Fluorophenyl methyl sulfide; m-Fluorothioanisole; Methyl 3-fluorophenyl sulfide; (3-Fluorophenyl)(methyl)sulfane
EINECS	211-509-6

Quality Control

Our 3-Fluorothioanisole is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure identity, purity, and consistency. We provide full traceability and detailed Certificates of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports your regulatory needs in cGMP and ISO 9001 environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.