Description

2-Bromo-4-(Trifluoromethyl)Benzyl Bromide is a versatile and highly reactive benzyl bromide derivative, serving as a critical bifunctional building block in advanced organic synthesis. Its molecular structure, featuring both a reactive benzyl bromide and a bromo-trifluoromethyl substituted aromatic ring, makes it indispensable for constructing complex molecules with tailored properties. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules requiring a trifluoromethylphenyl moiety.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and pesticides, where the CF3 group enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a starting material for synthesizing specialized phosphine ligands or metal-organic frameworks (MOFs) used in catalysis.
• Material Science: Building block for creating specialty polymers, liquid crystals, or organic electronic materials with unique optical or electronic properties.
• Cross-Coupling Reactions: Valuable substrate in Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions due to the presence of an aromatic bromine atom.
• Derivatization Agent: The benzyl bromide group allows for efficient alkylation of nucleophiles like amines, alcohols, and carboxylic acids, facilitating molecular diversification.

Basic Information

Product Name	2-Bromo-4-(Trifluoromethyl)Benzyl Bromide
CAS No.	657-64-7
Molecular Formula	C8H5Br2F3
Molecular Weight	317.93 g/mol
Synonyms	α,2-Dibromo-α-(trifluoromethyl)toluene; (2-Bromo-4-(trifluoromethyl)phenyl)methyl bromide; 1-(Bromomethyl)-2-bromo-4-(trifluoromethyl)benzene; Benzene, 1-(bromomethyl)-2-bromo-4-(trifluoromethyl)-; 2-Bromo-α-(bromomethyl)-4-(trifluoromethyl)toluene; 4-Trifluoromethyl-2-bromobenzyl bromide
EINECS	211-503-4

Quality Control

Our 2-Bromo-4-(Trifluoromethyl)Benzyl Bromide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the exacting standards required for research and scale-up applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its reactivity as a benzyl bromide derivative and sensitivity to light, prolonged exposure to light or moisture should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.