Description

5-Chloro-2-(Trifluoromethyl)Benzimidazole is a versatile and high-value heterocyclic building block characterized by its unique halogenated and fluorinated structure. This compound is critical for the synthesis of advanced materials and active pharmaceutical ingredients (APIs) due to its ability to impart specific electronic and steric properties. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for developing novel compounds with targeted functionalities.

Application

• Pharmaceutical Intermediate: A key synthon in the research and production of novel drug candidates, particularly for kinase inhibitors and antiviral agents.
• Agrochemical Synthesis: Used in the development of advanced herbicides and fungicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Material Science Research: Serves as a precursor for organic electronic materials, such as ligands for metal-organic frameworks (MOFs) or components in organic light-emitting diodes (OLEDs).
• Dye and Pigment Manufacturing: Acts as an intermediate for creating specialized heterocyclic dyes with improved light-fastness and color properties.
• Chemical Research & Development: Employed as a versatile scaffold in medicinal chemistry and process chemistry for structure-activity relationship (SAR) studies.

Basic Information

Product Name	5-Chloro-2-(Trifluoromethyl)Benzimidazole
CAS No.	656-49-5
Molecular Formula	C8H4ClF3N2
Molecular Weight	220.58 g/mol
Synonyms	5-Chloro-2-(trifluoromethyl)-1H-benzimidazole; 2-(Trifluoromethyl)-5-chlorobenzimidazole; 5-Chloro-2-trifluoromethylbenzimidazole; 1H-Benzimidazole, 5-chloro-2-(trifluoromethyl)-; 656-49-5; 5-Chloro-2-(trifluoromethyl)-1H-benzo[d]imidazole; Benzimidazole, 5-chloro-2-(trifluoromethyl)-
EINECS	Contact for details

Quality Control

Our 5-Chloro-2-(Trifluoromethyl)Benzimidazole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for each lot, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your most critical synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.