Description

2-Fluorophenylmethylsulfone is a versatile organosulfur compound featuring a sulfone functional group and a fluorine substituent on the aromatic ring. This unique structure makes it a valuable building block and intermediate in advanced organic synthesis, particularly for pharmaceuticals and agrochemicals. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, crop protection, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key synthon for the development of new drug candidates, especially in kinase inhibitors and CNS-active molecules.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides and fungicides, leveraging the fluorine atom for enhanced bioactivity.
• Ligand & Catalyst Development: Serves as a precursor for sulfone-containing ligands used in transition metal catalysis and asymmetric synthesis.
• Material Science Research: Investigated as a monomer or additive for high-performance polymers with specific thermal or solubility properties.
• Organic Electronics: Potential intermediate in the synthesis of charge-transport materials or emissive layers for OLEDs.
• Custom Synthesis & Contract Manufacturing: Supplied to CROs and CDMOs for client-specific research projects and scale-up campaigns.

Basic Information

Product Name	2-Fluorophenylmethylsulfone
CAS No.	654-47-7
Molecular Formula	C7H7FO2S
Molecular Weight	174.19 g/mol
Synonyms	(2-Fluorophenyl)(methyl)sulfone; 1-Fluoro-2-(methylsulfonyl)benzene; Methyl 2-fluorophenyl sulfone; 2-Fluorobenzylsulfone; 2-Fluorophenyl methyl sulphone; o-Fluorophenylmethylsulfone; 2-Fluoro Thioanisole S,S-Dioxide
EINECS	211-500-6

Quality Control

Our 2-Fluorophenylmethylsulfone is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and a detailed Certificate of Analysis (COA) with each shipment, confirming compliance with agreed specifications. Our quality commitment supports applications requiring high-purity intermediates for GLP or cGMP development work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.