Description

n-[n-[n-(Trifluoroacetyl)Glycyl]Glycyl]Glycine Methyl Ester is a specialized trifluoroacetyl-protected tripeptide derivative, serving as a critical building block in advanced organic synthesis. This compound matters for its role in facilitating the controlled assembly of peptide chains, where the trifluoroacetyl (TFA) group offers a robust yet selectively removable protecting strategy. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel peptides, peptidomimetics, and active pharmaceutical ingredients (APIs).

Application

• Peptide Synthesis Intermediate: A key protected intermediate in solid-phase and solution-phase peptide synthesis (SPPS).
• Pharmaceutical Research: Used in the R&D of therapeutic peptides and bioactive molecules.
• Bioconjugation Chemistry: Serves as a precursor for creating labeled peptides or peptide-drug conjugates.
• Chemical Biology Probes: Employed in the synthesis of probes for studying enzyme activity or protein-protein interactions.
• Material Science: Potential building block for designing peptide-based polymers or nanomaterials.
• Reference Standard: Used as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	n-[n-[n-(Trifluoroacetyl)Glycyl]Glycyl]Glycine Methyl Ester
CAS No.	651-18-3
Molecular Formula	C10H13F3N3O5
Molecular Weight	312.22 g/mol
Synonyms	N-(Trifluoroacetyl)triglycine methyl ester; N-(Trifluoroacetylglycylglycylglycine methyl ester; Glycine, N-[N-[N-(trifluoroacetyl)glycyl]glycyl]-, methyl ester; TFA-Gly-Gly-Gly-OMe; Trifluoroacetyl-triglycine methyl ester; Methyl N-[N-[N-(2,2,2-trifluoroacetyl)glycyl]glycyl]glycinate; 651-18-3
EINECS	Contact for details

Quality Control

Our n-[n-[n-(Trifluoroacetyl)Glycyl]Glycyl]Glycine Methyl Ester is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. Certificates of Analysis (COA) with detailed specifications are provided to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture uptake, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.