Description

4-[3-(2-Chloro-9H-Thioxanthen-9-Ylidene)Propyl]Piperazine-1-Ethanol Dihydrochloride is a high-purity, pharmacologically active compound primarily used as a key intermediate in advanced pharmaceutical synthesis. This compound matters for its critical role in the development of specific therapeutic agents, requiring stringent quality control to ensure downstream product efficacy and safety. It is essential for R&D laboratories and manufacturing facilities in the pharmaceutical and fine chemical industries focused on producing innovative active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of specific therapeutic compounds, particularly in central nervous system (CNS) drug research.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core structural component for the development and scale-up of novel APIs.
• Biochemical Research: Used in pharmacological studies and as a reference standard in analytical method development for drug discovery.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis for creating complex, high-value specialty chemicals.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials.

Basic Information

Item	Detail
Product Name	4-[3-(2-Chloro-9H-Thioxanthen-9-Ylidene)Propyl]Piperazine-1-Ethanol Dihydrochloride
CAS No.	633-59-0
Molecular Formula	C22H26Cl2N2OS
Molecular Weight	437.42 g/mol
Synonyms	Clopenthixol Impurity; 2-Chloro-9-[3-[4-(2-hydroxyethyl)piperazin-1-yl]propylidene]thioxanthene Dihydrochloride; Clopenthixol Related Compound; 4-[3-(2-Chloro-9H-thioxanthen-9-ylidene)propyl]-1-piperazineethanol Dihydrochloride; 1-Piperazineethanol, 4-[3-(2-chloro-9H-thioxanthen-9-ylidene)propyl]-, dihydrochloride; Clopenthixol Dihydrochloride Impurity; Thioxanthene Derivative
EINECS	Contact for details

Quality Control

Our 4-[3-(2-Chloro-9H-Thioxanthen-9-Ylidene)Propyl]Piperazine-1-Ethanol Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing all specifications and test results. We support compliance with cGMP, ICH Q7, and other relevant pharmaceutical guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a low-humidity environment to prevent moisture absorption. For long-term storage, consider desiccants or inert atmosphere packaging.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.