Description

3-Ethoxyprop-1-yne is a versatile alkyne ether compound valued for its unique reactivity as a protected propargylic alcohol derivative. This chemical serves as a crucial building block in advanced organic synthesis, enabling the construction of complex molecular architectures. It is primarily utilized by pharmaceutical intermediates manufacturers and fine chemical research laboratories for developing active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of complex drug molecules, particularly those requiring propargylic ether functionalities.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides where its alkyne group enables specific cyclization reactions.
• Material Science Research: Acts as a monomer or cross-linking agent in the development of specialty polymers and resins with tailored properties.
• Organic Synthesis: Employed in Sonogashira coupling and other palladium-catalyzed reactions to introduce ethoxyacetylene units.
• Ligand and Catalyst Preparation: Useful for modifying ligands and creating novel organometallic catalysts for asymmetric synthesis.
• Flavor and Fragrance Industry: Serves as a precursor for synthesizing specific aroma chemicals and flavoring agents.

Basic Information

Product Name	3-Ethoxyprop-1-yne
CAS No.	628-33-1
Molecular Formula	C5H8O
Molecular Weight	84.12 g/mol
Synonyms	3-Ethoxy-1-propyne; Ethoxyacetylene; Ethyl propargyl ether; 1-Ethoxy-2-propyne; Propargyl ethyl ether; 3-Ethoxypropylene; 2-Propynyl ethyl ether; EINECS 211-032-0
EINECS	211-032-0

Quality Control

Our 3-Ethoxyprop-1-yne is produced under stringent quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including GC, NMR, and FTIR analysis, to verify identity and purity. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, well-ventilated area away from heat sources and incompatible materials. Due to its highly volatile nature, keep containers tightly sealed when not in use. Recommended storage temperature is 2-8°C for extended stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to reference spectrum
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.405 - 1.415
Density (20°C)	0.85 - 0.87 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.