Description

4-Chlorobutyronitrile is a versatile bifunctional organic intermediate containing both a reactive nitrile group and a chloromethyl moiety. This compound matters for its crucial role in the synthesis of complex molecules, particularly in the pharmaceutical and agrochemical sectors, where it serves as a key building block. Industries such as fine chemical manufacturing, pharmaceutical R&D, and material science need this high-purity intermediate for constructing pyrrolidines, cyclopropanes, and other heterocyclic frameworks essential for active ingredients.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various active pharmaceutical ingredients (APIs), including GABAergic agents and other neurologically active compounds.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators, leveraging its reactive sites for structural diversification.
• Fine Chemical Building Block: Employed in organic synthesis for constructing pyrrolidine and other nitrogen-containing heterocycles, which are prevalent in many specialty chemicals.
• Material Science Research: Serves as a monomer or cross-linking agent in the development of specialty polymers and functional materials.
• Chemical Research & Development: Utilized in academic and industrial labs for method development and the synthesis of novel chemical entities.

Basic Information

Product Name	4-Chlorobutyronitrile
CAS No.	628-20-6
Molecular Formula	C4H6ClN
Molecular Weight	103.55 g/mol
Synonyms	4-Chlorobutanenitrile; γ-Chlorobutyronitrile; 1-Chloro-3-cyanopropane; Butyronitrile, 4-chloro-; NSC 9375; 4-Chloro-butyronitril; 4-Chlorbutyronitril
EINECS	211-031-2

Quality Control

Our 4-Chlorobutyronitrile is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including GC, HPLC, and NMR, to ensure high chemical purity and consistency. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong acids, bases, and oxidizing agents. Recommended storage temperature is between 15°C and 25°C. Keep container tightly sealed when not in use to prevent moisture absorption and volatilization.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.4420 - 1.4460
Density (20°C)	1.150 - 1.170 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.