Description

Crotonamide (CAS NO 625-37-6) is a versatile and reactive α,β-unsaturated amide, serving as a crucial synthetic intermediate in advanced organic chemistry. Its conjugated system makes it a valuable electrophile for Michael additions and a precursor for heterocyclic compounds, enabling the construction of complex molecular architectures. This high-purity building block is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, where reliable quality and consistent supply are paramount for process development and scale-up.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds containing pyrrolidine, pyridine, or other nitrogen-containing heterocycles.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators, leveraging its reactivity to create novel bioactive molecules.
• Polymer Chemistry: Acts as a monomer or co-monomer precursor for specialty polymers, including polyamides and materials with specific thermal or mechanical properties.
• Organic Synthesis Reagent: Employed in academic and industrial R&D for Michael addition reactions, cycloadditions, and as a precursor to crotonic acid derivatives.
• Chemical Research: Serves as a standard or starting material in methodological development and catalysis studies within fine chemical laboratories.

Basic Information

Product Name	Crotonamide
CAS No.	625-37-6
Molecular Formula	C4H7NO
Molecular Weight	85.10 g/mol
Synonyms	trans-Crotonamide; (E)-Crotonamide; 2-Butenamide; (E)-2-Butenamide; trans-2-Butenamide; Crotonic acid amide; NSC 9376; TIMTEC-BB SBB004336
EINECS	210-888-6

Quality Control

Our Crotonamide is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including identity confirmation by FT-IR, purity assessment by HPLC or GC, and control of residual solvents and moisture content to ensure it meets the high standards required for synthetic applications. A detailed Certificate of Analysis (COA) is provided with each shipment, guaranteeing traceability, consistency, and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect product quality and stability. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC/GC)	≥ 98.0%
Melting Point	158°C - 162°C
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.