Description

1-Phenyl-1-Propyne (CAS NO 623-32-5) is a versatile terminal alkyne building block characterized by its phenyl-substituted acetylene structure, making it a valuable synthon in advanced organic synthesis. Its primary commercial value lies in its role as a key precursor for constructing complex molecular architectures, particularly in pharmaceutical and materials science research. This compound is essential for R&D chemists and process development scientists in the fine chemical, agrochemical, and advanced material industries seeking to introduce alkyne functionality into target molecules.

Application

• Pharmaceutical Intermediates: Serves as a crucial building block in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly for Sonogashira and other cross-coupling reactions.
• Agrochemical Synthesis: Used in the research and development of novel pesticides, herbicides, and plant growth regulators where the alkyne moiety is integral to biological activity.
• Material Science & Polymer Chemistry: Acts as a monomer or functionalizing agent in the development of specialty polymers, conductive materials, and metal-organic frameworks (MOFs).
• Ligand & Catalyst Development: Employed in the preparation of specialized ligands for transition metal catalysis and organometallic complexes.
• Chemical Research & Development: A fundamental reagent in academic and industrial laboratories for exploring new organic transformations and synthetic methodologies.
• Fine Chemical Production: Utilized in the multi-step synthesis of complex fragrance compounds, dyes, and other high-value specialty chemicals.

Basic Information

Product Name	1-Phenyl-1-Propyne
CAS No.	623-32-5
Molecular Formula	C9H8
Molecular Weight	116.16 g/mol
Synonyms	Phenylmethylacetylene; 3-Phenyl-1-propyne; 1-Phenylpropylene; Methylphenylacetylene; Benzylacetylene; (Phenylethynyl)methane; Propyne, 1-phenyl-; 1-Phenylpropyne
EINECS	210-788-2

Quality Control

Our 1-Phenyl-1-Propyne is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive quality assurance, with products typically meeting a purity specification of ≥97% (GC) for standard research grades. Higher purity grades are available upon request. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and relevant physical parameters. Our quality protocols are designed to support compliance in cGMP and ISO 9001 environments where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is between 2°C and 25°C. Keep container tightly sealed when not in use to prevent evaporation and minimize exposure to moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Refractive Index (n20D)	1.525 - 1.535
Density (20°C)	0.90 - 0.92 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.