Description

4-Hydroxy Mepivacaine is a key pharmaceutical intermediate and metabolite of the local anesthetic mepivacaine. This compound is critical for research and development in pharmacology and analytical chemistry, particularly in metabolic pathway studies and impurity profiling. It is primarily utilized by pharmaceutical manufacturers, contract research organizations (CROs), and analytical laboratories involved in drug development and quality control.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis and research of anesthetic agents and their derivatives.
• Metabolite Reference Standard: Used as an analytical standard in bioanalytical studies to identify and quantify mepivacaine metabolites in biological samples.
• Impurity Standard: Essential for the development and validation of analytical methods (e.g., HPLC, LC-MS) to control the quality and purity of mepivacaine-based drug substances.
• Pharmacological Research: Employed in preclinical studies to investigate the metabolism, pharmacokinetics, and safety profile of mepivacaine.
• Chemical Synthesis: Acts as a starting material or precursor for the synthesis of novel chemical entities with potential therapeutic applications.

Basic Information

Product Name	4-Hydroxy Mepivacaine
CAS No.	616-66-0
Molecular Formula	C15H22N2O2
Molecular Weight	262.35 g/mol
Synonyms	4-Hydroxymepivacaine; 1-Methyl-2',6'-pipecoloxylidide-4'-ol; N-(2,6-Dimethylphenyl)-1-methyl-4-piperidinecarboxamide, 4-hydroxy-; Mepivacaine Hydroxy Metabolite; Mepivacaine, 4'-hydroxy-; 4'-Hydroxymepivacaine; 4-Hydroxy-1-methyl-2',6'-pipecoloxylidide
EINECS	Contact for details

Quality Control

Our 4-Hydroxy Mepivacaine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical research and development. A detailed Certificate of Analysis (COA) providing specifications for identity, purity, and impurities is supplied with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.