Description

2-Nitrobenzonitrile CAS NO 612-24-8 is a versatile aromatic nitrile derivative that serves as a critical building block in advanced organic synthesis. Its structure, featuring both a nitrile and a nitro group, makes it a valuable precursor for the production of more complex heterocyclic compounds and functionalized intermediates. This compound is essential for research and development chemists, as well as production units, in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop new active ingredients and performance materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various heterocyclic compounds, including quinazolines, benzimidazoles, and other nitrogen-containing scaffolds with potential biological activity.
• Agrochemical Synthesis: Used in the manufacture of herbicides, fungicides, and insecticides, where the nitro and nitrile functionalities are transformed into amines, amides, or other active moieties.
• Dye and Pigment Manufacturing: Serves as a starting material for the production of azo dyes and complex organic pigments, contributing to color strength and stability.
• Material Science Research: Employed in the development of organic semiconductors, liquid crystals, and polymers where specific electronic properties are required.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed reactions, such as Suzuki or Buchwald-Hartwig amination, for creating biaryl structures.
• Chemical Research & Development: A standard reagent in academic and industrial R&D labs for methodological studies and exploring new synthetic pathways.

Basic Information

Product Name	2-Nitrobenzonitrile
CAS No.	612-24-8
Molecular Formula	C7H4N2O2
Molecular Weight	148.12 g/mol
Synonyms	o-Nitrobenzonitrile; 2-Nitrobenzenecarbonitrile; Benzonitrile, 2-nitro-; (2-Nitrophenyl)cyanide; 2-Cyanonitrobenzene; NSC 404026; USAF EK-7005; CCRIS 6051
EINECS	210-287-5

Quality Control

Our 2-Nitrobenzonitrile is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for synthetic applications. We provide Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Custom purity grades, including high-purity research grades, are available to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, the container should be opaque or stored in a dark place.

Specification

Item	Specification
Appearance	Yellow to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	108°C - 112°C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.