Description

Triphenylphosphine is a versatile organophosphorus compound widely recognized as a crucial ligand in transition metal catalysis and a valuable reagent in organic synthesis. Its primary commercial value lies in its ability to facilitate key chemical transformations, including the Wittig reaction for olefin synthesis and various cross-coupling processes. This makes it an indispensable material for research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, where precise molecular construction is paramount.

Application

• As a key ligand in transition metal-catalyzed cross-coupling reactions (e.g., Suzuki, Heck, Stille).
• As the essential phosphorus ylide precursor in the Wittig reaction for the synthesis of alkenes and natural products.
• As a reducing agent for organic peroxides to alcohols and in the Mitsunobu reaction for esterification and etherification.
• In the manufacture of photoinitiators and catalysts for polymer production.
• As a stabilizer and intermediate in the synthesis of flame retardants and plastic additives.
• In pharmaceutical synthesis for constructing complex drug molecules and active pharmaceutical ingredients (APIs).
• For the preparation of quaternary phosphonium salts, used as phase-transfer catalysts and ionic liquids.

Basic Information

Product Name	Triphenylphosphine
CAS No.	605-35-0
Molecular Formula	C18H15P
Molecular Weight	262.29 g/mol
Synonyms	Triphenylphosphane; Phosphorous Triphenyl; TPP; PPh3; Triphenyl Phosphine; (C6H5)3P; Celluflex TPP; NSC 3636
EINECS	210-036-0

Quality Control

Our Triphenylphosphine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, melting point, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, supporting its use in regulated synthesis pathways.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to handle and store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation, especially after opening the original container.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Assay (HPLC)	≥ 99.0%
Melting Point	79 - 82 °C
Loss on Drying	≤ 0.5 %
Residue on Ignition	≤ 0.1 %

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.