Description

2-Chloro-α,N,n-Trimethyl-10H-Phenothiazine-10-Ethanamine is a high-purity phenothiazine derivative, a critical advanced intermediate in the synthesis of complex pharmaceutical compounds. This compound matters for its role in developing active pharmaceutical ingredients (APIs) with specific neurological and antihistaminic properties, where precise chemical structure is paramount. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development and production of specialty drugs, requiring a reliable and consistent supply of high-quality building blocks.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of tricyclic antidepressant and antipsychotic drug candidates.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in the production pathway for specific phenothiazine-class APIs.
• Chemical Research & Development: Serves as a crucial reagent in medicinal chemistry for creating novel therapeutic molecules.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Dye and Pigment Intermediate: Potential use in the synthesis of specialized dyes and organic pigments due to the phenothiazine core.

Basic Information

Product Name	2-Chloro-α,N,n-Trimethyl-10H-Phenothiazine-10-Ethanamine
CAS No.	604-73-9
Molecular Formula	C₁₇H₁₉ClN₂S
Molecular Weight	318.86 g/mol
Synonyms	2-Chloro-10-[2-(dimethylamino)propyl]phenothiazine; 2-Chlorpromazine; 2-Chloro-N,N-dimethyl-10H-phenothiazine-10-propanamine; 604-73-9; 2-Chloro-10-(3-dimethylaminopropyl)phenothiazine; NSC 70939; 2-CPZ
EINECS	Contact for details

Quality Control

Our 2-Chloro-α,N,n-Trimethyl-10H-Phenothiazine-10-Ethanamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical intermediate applications. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.