Description

Fluphenazine is a high-potency phenothiazine derivative belonging to the class of typical antipsychotic agents. Its primary value lies in its potent dopamine receptor antagonism, making it a critical active pharmaceutical ingredient (API) for the formulation of long-acting injectable neuroleptic medications. This compound is essential for manufacturers in the global pharmaceutical industry developing treatments for chronic psychotic disorders such as schizophrenia, where sustained therapeutic action is required. We supply high-purity Fluphenazine CAS NO 69-23-8 to meet the stringent demands of GMP-compliant drug production.

Application

• Pharmaceutical API: Primary use as the active ingredient in long-acting injectable antipsychotic formulations (e.g., Fluphenazine Decanoate, Fluphenazine Enanthate).
• Neuroleptic Drug Synthesis: Key intermediate in the synthesis of various fluphenazine ester prodrugs designed for depot injections.
• Psychiatric Medication Manufacturing: Used in the production of tablets and oral solutions for the management of psychotic symptoms.
• Research & Development: Reference standard and biochemical tool in neuroscience research for studying dopamine D2 receptor pharmacology.
• Veterinary Medicine: Potential application in veterinary behavioral medicine for managing agitation in animals, subject to regional approvals.
• Controlled-Release Drug Delivery Systems: Investigational use in advanced drug delivery platforms aiming for sustained release profiles.

Basic Information

Product Name	Fluphenazine
CAS No.	69-23-8
Molecular Formula	C₂₂H₂₆F₃N₃OS
Molecular Weight	437.52 g/mol
Synonyms	Fluphenazine Base; 4-[3-[2-(Trifluoromethyl)-10H-phenothiazin-10-yl]propyl]-1-piperazineethanol; Prolixin; Permitil; Anatensol; Lyogen; Moditen; Pacinol; Dapotum; Fludecate; Flufenazin; Trifluoperazine (related compound)
EINECS	200-700-6

Quality Control

Our Fluphenazine is manufactured under strict quality management systems to ensure it meets the exacting standards for pharmaceutical active ingredients. Each batch is subjected to comprehensive analytical testing, including identity confirmation, purity assay, and impurity profiling via advanced techniques like HPLC and GC. We provide full traceability and Certificates of Analysis (COA) that detail compliance with in-house specifications aligned with major pharmacopoeial guidelines (USP/EP). Our commitment to cGMP principles ensures consistency, reliability, and regulatory support for our global clientele.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The product is light-sensitive (store away from light). Keep the container tightly sealed to protect from moisture. Store away from incompatible materials and out of direct sunlight.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 1.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.