Description

4-Chlorobenzonitrile is a versatile aromatic nitrile derivative that serves as a critical building block in advanced organic synthesis. Its value lies in the reactive nitrile and chloro functional groups, which enable precise chemical transformations for creating complex molecular architectures. This high-purity intermediate is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to develop active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various active pharmaceutical ingredients (APIs), including potential kinase inhibitors and other therapeutic compounds.
• Agrochemical Synthesis: Used in the manufacturing of herbicides, fungicides, and pesticides, leveraging its structure to introduce specific biological activity.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Polymer and Material Science: Acts as a monomer or modifier in the production of high-performance polymers, resins, and liquid crystals.
• Dyestuff and Pigment Manufacturing: Employed in the synthesis of complex dyes and organic pigments due to its aromatic backbone.
• Organic Synthesis Building Block: Utilized in cross-coupling reactions (e.g., Suzuki, Sonogashira) and cyanation processes to construct more complex benzonitrile derivatives.

Basic Information

Product Name	4-Chlorobenzonitrile
CAS No.	623-03-0
Molecular Formula	C7H4ClN
Molecular Weight	137.57 g/mol
Synonyms	p-Chlorobenzonitrile; 4-Chlorobenzene carbonitrile; 1-Chloro-4-cyanobenzene; p-Cyanochlorobenzene; 4-Chlorophenyl cyanide; Benzonitrile, 4-chloro-; NSC 6055; p-Chlorobenzyl nitrile
EINECS	210-775-9

Quality Control

Our 4-Chlorobenzonitrile is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency suitable for demanding synthetic applications. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents, strong bases, and sources of ignition.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Melting Point	92°C - 96°C
Loss on Drying	≤0.5%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.