Description

Bretylium Tosylate is an organic salt compound, specifically the tosylate salt of bretylium, with the CAS registry number 61-75-6. This compound is a critical pharmaceutical intermediate and research chemical, valued for its role in the synthesis and development of specialized active pharmaceutical ingredients (APIs). It is primarily utilized by research institutions, pharmaceutical manufacturers, and fine chemical producers engaged in cardiovascular and neurological research, as well as in the production of high-purity reference standards.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of bretylium-based active pharmaceutical ingredients (APIs) for research and development.
• Research & Development: Used as a reference standard and biochemical tool in cardiovascular and autonomic nervous system research.
• Fine Chemical Synthesis: Employed in organic synthesis for the preparation of complex molecules requiring a quaternary ammonium tosylate moiety.
• Analytical Standard: Serves as a high-purity calibration standard for analytical methods such as HPLC and LC-MS in quality control laboratories.

Basic Information

Product Name	Bretylium Tosylate
CAS No.	61-75-6
Molecular Formula	C18H24NO3S
Molecular Weight	334.46 g/mol
Synonyms	Bretylium tosilate; Bretylium p-toluenesulfonate; N-Ethyl-N,N-dimethyl-2-bromobenzylammonium p-toluenesulfonate; 2-Bromo-N-ethyl-N,N-dimethylbenzenemethanaminium 4-methylbenzenesulfonate; Bretylate; Bretylol Tosylate; Darenthin Tosylate; Ornid Tosylate
EINECS	200-517-6

Quality Control

Our Bretylium Tosylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical intermediates and research chemicals. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting key parameters such as assay, related substances, and residual solvents.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent absorption of atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.