Description

(-)-10-(3-[Dimethylamino]-2-Methylpropyl)-2-Methoxy-Phenothiazine Maleate Salt CAS NO 60-99-1 is a high-purity phenothiazine derivative, specifically formulated as a maleate salt to enhance stability and handling properties. This compound is a critical intermediate in the synthesis of advanced pharmaceutical agents, particularly those targeting the central nervous system. It is essential for research and development laboratories, fine chemical synthesis, and the production of active pharmaceutical ingredients (APIs) requiring precise stereochemistry and purity.

Application

• Pharmaceutical Intermediate: A key chiral building block in the synthesis of neuroleptic and antipsychotic drug candidates.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the development of new phenothiazine-based therapeutics.
• Fine Chemical Synthesis: Serves as a precursor for creating more complex molecules with specific pharmacological activity.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Biochemical Research: Utilized in studies investigating dopamine receptor interactions and related neurological pathways.

Basic Information

Item	Details
Product Name	(-)-10-(3-[Dimethylamino]-2-Methylpropyl)-2-Methoxy-Phenothiazine Maleate Salt
CAS No.	60-99-1
Molecular Formula	C21H26N2O2S • C4H4O4
Molecular Weight	478.55 g/mol
Synonyms	Levomepromazine Maleate; Methotrimeprazine Maleate; (-)-Methotrimeprazine Maleate; Levoprome Maleate; Nozinan Maleate; 7040 R.P. Maleate; 2-Methoxy-10-(2-methyl-3-dimethylaminopropyl)phenothiazine Maleate; (2R)-3-(2-Methoxyphenothiazin-10-yl)-N,N,2-trimethylpropan-1-amine (Z)-but-2-enedioate
EINECS	Contact for details

Quality Control

Our (-)-10-(3-[Dimethylamino]-2-Methylpropyl)-2-Methoxy-Phenothiazine Maleate Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the stringent requirements for pharmaceutical R&D and synthesis. A Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0% (anhydrous basis)
Chiral Purity (HPLC)	≥99.0%
Water Content (KF)	≤2.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.