Description

1H-Pyrrole-3-Carbonitrile, 1-Acetyl-2-Amino-4,5-Dihydro-4-Oxo- (9Ci) is a high-purity, heterocyclic organic building block of significant interest in advanced chemical synthesis. This compound matters for its role as a versatile precursor in the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is primarily needed by R&D chemists and process development scientists working on novel active ingredients, where its unique pyrrole-carbonitrile-oxo scaffold enables the construction of sophisticated nitrogen-containing heterocycles.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the creation of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Material Science Research: Serves as a precursor for functionalized polymers or organic electronic materials due to its electron-withdrawing nitrile and carbonyl groups.
• Chemical Biology Probes: Employed in the synthesis of molecular probes and inhibitors for studying enzyme mechanisms and biological pathways.
• Custom Synthesis & Contract Manufacturing: A critical starting material for fine chemical manufacturers offering bespoke synthesis services to the life sciences industry.

Basic Information

Product Name	1H-Pyrrole-3-Carbonitrile, 1-Acetyl-2-Amino-4,5-Dihydro-4-Oxo- (9Ci)
CAS No.	590374-61-1
Molecular Formula	C7H7N3O2
Molecular Weight	165.15 g/mol
Synonyms	1-Acetyl-2-amino-4,5-dihydro-4-oxo-1H-pyrrole-3-carbonitrile; 2-Amino-1-acetyl-4,5-dihydro-4-oxo-1H-pyrrole-3-carbonitrile; 1-Acetyl-2-amino-4,5-dihydro-4-oxopyrrole-3-carbonitrile; 3-Cyano-1-acetyl-2-amino-4,5-dihydro-4-oxopyrrole; 590374-61-1; 1H-Pyrrole-3-carbonitrile, 1-acetyl-2-amino-4,5-dihydro-4-oxo- (9CI)
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized and controlled using advanced analytical techniques to guarantee identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for purity, impurities, and other critical parameters are available upon request. We adhere to a cGMP-compliant quality management system to support our clients in regulated development pipelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive (hygroscopic) and should be handled under an inert atmosphere for prolonged operations to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.