Description

Benzeneacetonitrile, 2-Fluoro-6-Methyl-α-Oxo- (9Ci) is a specialized fluorinated aromatic nitrile building block, distinguished by its unique keto and cyano functional groups. This compound is of significant value in advanced organic synthesis, particularly for constructing complex molecular architectures in pharmaceutical and agrochemical research. It serves as a critical intermediate for medicinal chemists and R&D professionals developing novel active ingredients, where its structure enables precise modifications to enhance biological activity and selectivity.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and anti-inflammatory targets.
• Agrochemical Synthesis: Used in the creation of advanced herbicides and pesticides, leveraging the fluorine atom for improved metabolic stability and efficacy.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the development of organic electronic materials and advanced polymers with tailored properties.
• Chemical Biology Probes: Utilized as a building block for fluorescent tags and activity-based probes in biochemical research.

Basic Information

Product Name	Benzeneacetonitrile, 2-Fluoro-6-Methyl-α-Oxo- (9Ci)
CAS No.	590368-96-0
Molecular Formula	C10H8FNO2
Molecular Weight	193.18 g/mol
Synonyms	2-Fluoro-6-methyl-α-oxobenzeneacetonitrile; 2-(2-Fluoro-6-methylphenyl)-2-oxoacetonitrile; α-Oxo-2-fluoro-6-methylbenzeneacetonitrile; 2-Fluoro-6-methylbenzoyl cyanide; (2-Fluoro-6-methylphenyl)(oxo)acetonitrile; 2-Fluoro-6-methylphenacyl cyanide; 590368-96-0 (CAS Registry)
EINECS	Contact for details

Quality Control

Our Benzeneacetonitrile, 2-Fluoro-6-Methyl-α-Oxo- (9Ci) is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency essential for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). This material is light-sensitive and should be handled and stored accordingly to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.