Description

Leucine, n-Acetyl-2-(2-Methylpropyl)- is a chemically modified derivative of the essential amino acid L-leucine, characterized by its specific acetyl and isobutyl substituents. This compound is valued for its role as a key chiral building block and intermediate in the synthesis of more complex bioactive molecules, particularly in pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for creating novel peptide-based therapeutics and other high-value compounds.

Application

• Pharmaceutical Intermediate: A critical chiral synthon in the research and production of peptide-based drugs and active pharmaceutical ingredients (APIs).
• Biochemical Research: Used as a standard or reagent in enzymatic studies, metabolic pathway analysis, and proteomics research.
• Fine Chemical Synthesis: Serves as a specialized building block for constructing complex organic molecules with specific stereochemistry in custom synthesis projects.
• Nutraceutical Development: Investigated for potential applications in designing advanced amino acid supplements and specialized nutritional formulations.

Basic Information

Product Name	Leucine, n-Acetyl-2-(2-Methylpropyl)-
CAS No.	588708-33-2
Molecular Formula	C11H21NO3
Molecular Weight	215.29 g/mol
Synonyms	N-Acetyl-2-(2-methylpropyl)leucine; N-Acetyl-2-isobutylleucine; 2-(2-Methylpropyl)-N-acetylleucine; (2S)-2-Acetamido-4-methylpentanoic acid (related isomer); Ac-Leu-OH derivative; N-Acetyl-leucine analog; 588708-33-2; Leucine, N-acetyl-2-(2-methylpropyl)-
EINECS	Contact for details

Quality Control

Our Leucine, n-Acetyl-2-(2-Methylpropyl)- is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including identity confirmation by spectroscopic methods and purity assessment by chromatography, to ensure it meets the high standards required for research and synthesis. A Certificate of Analysis (COA) detailing specific results for identity, assay, and purity is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed to minimize exposure to atmospheric humidity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Optical Rotation	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.