Description

(9H-Fluoren-9-Yl)Methyl (3-Ethynylphenyl)Carbamate is a specialized carbamate derivative featuring both a fluorenylmethyl (Fmoc) protecting group and an ethynylphenyl moiety. This compound matters as a key synthetic intermediate and building block in advanced organic synthesis, particularly for the development of pharmaceuticals and functional materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of active pharmaceutical ingredients (APIs), especially those requiring Fmoc-protected amine chemistry or alkyne-based click chemistry.
• Peptide Synthesis: Acts as a protected amino acid derivative or a reagent for introducing specific functional groups during solid-phase peptide synthesis (SPPS).
• Polymer Chemistry: Used as a monomer or functionalization agent for creating specialty polymers with tailored properties via its reactive alkyne group.
• Bioconjugation: Facilitates the site-specific labeling of biomolecules (proteins, antibodies, nucleic acids) through copper-catalyzed azide-alkyne cycloaddition (CuAAC) reactions.
• Chemical Probe Development: Employed in medicinal chemistry for the design and synthesis of molecular probes to study biological targets and pathways.
• Material Science Research: Utilized in the development of novel organic electronic materials, sensors, and coatings that incorporate conjugated systems.

Basic Information

Product Name	(9H-Fluoren-9-Yl)Methyl (3-Ethynylphenyl)Carbamate
CAS No.	587878-72-6
Molecular Formula	C24H19NO3
Molecular Weight	369.42 g/mol
Synonyms	Fmoc-3-ethynylaniline; N-(3-Ethynylphenyl)carbamic acid 9H-fluoren-9-ylmethyl ester; 3-Ethynylphenyl (9-Fluorenylmethyl) carbamate; 9-Fluorenylmethyl N-(3-ethynylphenyl)carbamate; Carbamic acid, N-(3-ethynylphenyl)-, 9H-fluoren-9-ylmethyl ester; 587878-72-6; Fmoc-3-ethynyl aniline
EINECS	Contact for details

Quality Control

Our (9H-Fluoren-9-Yl)Methyl (3-Ethynylphenyl)Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.