Description

2-Aminocyclohexane-1-Carbonitrile is a versatile chiral amine derivative that serves as a critical building block in advanced organic synthesis. Its unique structure, featuring both amino and nitrile functional groups on a cyclohexane ring, makes it a valuable precursor for constructing complex, high-value molecules. This compound is primarily sought after by research and development laboratories and production facilities in the pharmaceutical and agrochemical sectors for the synthesis of active pharmaceutical ingredients (APIs) and specialized fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel therapeutic agents, including central nervous system (CNS) drugs and enzyme inhibitors.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its structural motif can contribute to biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to control stereochemistry.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, dyes, and functional materials requiring a rigid, substituted cyclohexyl backbone.
• Academic and Industrial Research: A valuable compound for methodological development in organic chemistry and medicinal chemistry research programs.

Basic Information

Product Name	2-Aminocyclohexane-1-Carbonitrile
CAS No.	586965-84-6
Molecular Formula	C7H12N2
Molecular Weight	124.18 g/mol
Synonyms	trans-2-Aminocyclohexanecarbonitrile; (1R,2R)-2-Aminocyclohexane-1-carbonitrile; (1S,2S)-2-Aminocyclohexane-1-carbonitrile; 2-Aminocyclohexanecarbonitrile; 1-Cyano-2-aminocyclohexane; 2-Amino-1-cyanocyclohexane; Cyclohexanecarbonitrile, 2-amino-; 2-Aminocyclohexyl cyanide
EINECS	Contact for details

Quality Control

Our 2-Aminocyclohexane-1-Carbonitrile is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chiral purity analysis, to ensure it meets the exacting standards required for pharmaceutical and fine chemical applications. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting purity, enantiomeric excess, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere if specified for the grade supplied.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% e.e. (for enantiomerically enriched grades)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.