Description

Ethyl (2E)-3-(4-Bromo-2-Fluorophenyl)Prop-2-Enoate is a high-purity, synthetic organic intermediate characterized by its bromo- and fluoro-substituted aromatic propenoate structure. This compound matters for its role as a critical building block in the synthesis of complex molecules, offering precise reactivity for constructing advanced chemical architectures. It is primarily needed by research and development teams, as well as process chemists, in the pharmaceutical and agrochemical industries for creating novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly for molecules targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Serves as a precursor in the manufacture of advanced herbicides and fungicides, leveraging the halogenated phenyl group for enhanced biological activity.
• Material Science Research: Used in the development of specialty polymers and liquid crystals, where the conjugated system and halogen atoms can influence material properties.
• Chemical Biology Probes: Employed in the synthesis of tagged molecules and probes for studying biological pathways and enzyme interactions.
• Custom Synthesis & Contract Manufacturing: A vital component for custom synthesis houses producing bespoke compounds for client-specific R&D projects.

Basic Information

Product Name	Ethyl (2E)-3-(4-Bromo-2-Fluorophenyl)Prop-2-Enoate
CAS No.	581778-88-3
Molecular Formula	C11H10BrFO2
Molecular Weight	273.10 g/mol
Synonyms	Ethyl (E)-3-(4-Bromo-2-fluorophenyl)acrylate; (E)-Ethyl 3-(4-bromo-2-fluorophenyl)acrylate; Ethyl 3-(4-Bromo-2-fluorophenyl)-2-propenoate; trans-Ethyl 3-(4-Bromo-2-fluorophenyl)acrylate; 2-Propenoic acid, 3-(4-bromo-2-fluorophenyl)-, ethyl ester, (2E)-; 4-Bromo-2-fluorocinnamic acid ethyl ester; Ethyl 4-Bromo-2-fluorocinnamate
EINECS	Contact for details

Quality Control

Our Ethyl (2E)-3-(4-Bromo-2-Fluorophenyl)Prop-2-Enoate undergoes rigorous quality testing to ensure compliance with industry standards for fine chemical intermediates. Production is managed under a cGMP-compliant quality management system, with strict in-process controls. Every batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles, available upon request. We ensure traceability and consistency to support your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and potential degradation. Handle and store in accordance with all applicable local and international regulations.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.