Description

L-Proline, 1-(Aminocarbonyl)-, Methyl Ester (9Ci) is a specialized proline derivative, a key building block in advanced organic synthesis and pharmaceutical research. This high-purity intermediate is critical for developing novel peptide-based therapeutics and fine chemicals, offering precise structural control. It is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and biotechnology sectors for the synthesis of complex molecules.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of novel peptide-based drugs, prodrugs, and active pharmaceutical ingredients (APIs).
• Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis to introduce modified proline residues, influencing peptide conformation and stability.
• Agrochemical Research: Serves as a key intermediate in the development of new herbicides, fungicides, and plant growth regulators with targeted activity.
• Bioconjugation & Probe Development: Employed in creating labeled peptides and molecular probes for biochemical assays and diagnostic applications.
• Academic & Industrial R&D: A valuable reagent for medicinal chemistry programs and exploring new chemical entities in life sciences research.
• Fine Chemical Synthesis: Used in the multi-step synthesis of complex chiral molecules requiring high stereochemical purity.

Basic Information

Product Name	L-Proline, 1-(Aminocarbonyl)-, Methyl Ester (9Ci)
CAS No.	578740-78-0
Molecular Formula	C7H12N2O3
Molecular Weight	172.18 g/mol
Synonyms	L-Proline, 1-carbamoyl-, methyl ester; Methyl 1-carbamoyl-L-prolinate; Methyl L-prolinate-1-carboxamide; 1-Carbamoylpyrrolidine-2-carboxylic acid methyl ester, (S)-; (S)-1-Carbamoyl-2-pyrrolidinecarboxylic acid methyl ester; (S)-Methyl 1-carbamoylpyrrolidine-2-carboxylate; L-Proline-1-carboxamide, methyl ester
EINECS	Contact for details

Quality Control

Our L-Proline, 1-(Aminocarbonyl)-, Methyl Ester (9Ci) is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, chiral analysis to confirm stereochemical integrity, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.