Description

n-Benzyl-4-Chloro-n-(1,1-Dioxidotetrahydrothiophen-3-Yl)-3-Nitrobenzamide is a high-purity, advanced pharmaceutical intermediate characterized by its complex sulfone and benzamide structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel therapeutic agents targeting specific biological pathways. It is primarily required by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in developing new active pharmaceutical ingredients (APIs) and bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of potential new drug candidates, especially those with sulfone-containing pharmacophores.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes during drug discovery.
• Protease Inhibitor Development: Acts as a precursor or core structure for molecules designed to inhibit specific enzymes like proteases.
• Chemical Biology Probes: Utilized in the creation of specialized probes for studying enzyme function and cellular signaling pathways.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CRMOs) for bespoke chemical synthesis projects.
• Academic Research: Used in university and institutional labs for advanced organic synthesis and methodological studies.

Basic Information

Product Name	n-Benzyl-4-Chloro-n-(1,1-Dioxidotetrahydrothiophen-3-Yl)-3-Nitrobenzamide
CAS No.	577996-11-3
Molecular Formula	C19H19ClN2O5S
Molecular Weight	422.88 g/mol
Synonyms	4-Chloro-N-benzyl-3-nitro-N-(1,1-dioxido-3-thiolanyl)benzamide; 3-Nitro-4-chloro-N-benzyl-N-(tetrahydro-1,1-dioxido-3-thienyl)benzamide; Benzamide, N-benzyl-4-chloro-N-(1,1-dioxidotetrahydro-3-thienyl)-3-nitro-; N-Benzyl-4-chloro-N-(1,1-dioxidotetrahydrothiophen-3-yl)-3-nitrobenzamide; 577996-11-3; UNII-9B8J2F8K8Q
EINECS	Contact for details

Quality Control

Our n-Benzyl-4-Chloro-n-(1,1-Dioxidotetrahydrothiophen-3-Yl)-3-Nitrobenzamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client requirements for research or cGMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.