Description

n-Butyl-2-[(2,3-Dihydro-1,4-Benzodioxin-6-Ylsulfonyl)-4-Fluoroanilino]Acetamide is a high-purity, advanced pharmaceutical intermediate characterized by its complex sulfonamide and benzodioxin structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel therapeutic agents targeting specific biological pathways. It is primarily required by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in drug discovery programs.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of new chemical entities (NCEs) for drug discovery.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize lead compounds.
• API Development: Serves as a precursor in the development of active pharmaceutical ingredients (APIs) with potential CNS or anti-inflammatory activity.
• Biochemical Tool Compound: Utilized in vitro and in vivo to study enzyme inhibition or receptor modulation.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis for creating complex, high-value molecules.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs for custom synthesis and scale-up projects.

Basic Information

Product Name	n-Butyl-2-[(2,3-Dihydro-1,4-Benzodioxin-6-Ylsulfonyl)-4-Fluoroanilino]Acetamide
CAS No.	577990-75-1
Molecular Formula	C20H23FN2O5S
Molecular Weight	422.47 g/mol
Synonyms	N-Butyl-2-[(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)(4-fluorophenyl)amino]acetamide; 2-[(2,3-Dihydro-1,4-benzodioxin-6-ylsulfonyl)(4-fluoroanilino)]-N-butylacetamide; 577990-75-1; Acetamide, N-butyl-2-[(2,3-dihydro-1,4-benzodioxin-6-ylsulfonyl)(4-fluorophenyl)amino]-; N-Butyl-2-((2,3-dihydrobenzo[b][1,4]dioxine-6-sulfonamido)(4-fluorophenyl))acetamide
EINECS	Contact for details

Quality Control

Our n-Butyl-2-[(2,3-Dihydro-1,4-Benzodioxin-6-Ylsulfonyl)-4-Fluoroanilino]Acetamide is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.