Description

3-Chloro-n-(3-Cyano-5,6,7,8-Tetrahydro-4H-Cyclohepta[B]Thien-2-Yl)Propanamide is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is of significant commercial importance for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is primarily sought by research institutions and pharmaceutical manufacturers engaged in drug discovery and process development.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of proprietary drug candidates, especially those targeting central nervous system (CNS) disorders or metabolic diseases.
• Drug Discovery Research: Serves as a versatile scaffold in medicinal chemistry for constructing compound libraries and exploring new structure-activity relationships (SAR).
• Process Chemistry Development: Used in the optimization and scale-up of synthetic routes for new chemical entities (NCEs) under Good Manufacturing Practice (GMP) conditions.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, specialized intermediates.
• Academic Research: Employed in university and institutional labs for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Item	Details
Product Name	3-Chloro-n-(3-Cyano-5,6,7,8-Tetrahydro-4H-Cyclohepta[B]Thien-2-Yl)Propanamide
CAS No.	574010-55-2
Molecular Formula	C15H17ClN2OS
Molecular Weight	308.82 g/mol
Synonyms	3-Chloro-N-(3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)propanamide; 3-Chloro-N-(3-cyano-5,6,7,8-tetrahydro-4H-cyclohepta[b]thiophen-2-yl)propanamide; 2-Propanamide, 3-chloro-N-(3-cyano-5,6,7,8-tetrahydro-4H-cyclohepta[b]thien-2-yl)-; Propanamide, 3-chloro-N-(3-cyano-4,5,6,7-tetrahydro-1-benzothien-2-yl)-; CAS 574010-55-2
EINECS	Contact for details

Quality Control

Our production of 3-Chloro-n-(3-Cyano-5,6,7,8-Tetrahydro-4H-Cyclohepta[B]Thien-2-Yl)Propanamide adheres to stringent quality management systems to ensure batch-to-batch consistency and reliability. All material is subjected to rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment. We support compliance with ICH guidelines and can tailor quality protocols to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound may be hygroscopic; therefore, containers should be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.