Description

4-Amino-3-Chloro-2-Methylbenzonitrile is a high-purity, versatile aromatic nitrile derivative that serves as a critical building block in advanced organic synthesis. Its unique substitution pattern makes it a valuable intermediate for creating complex molecules with specific functionalities. This compound is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting specific receptors or enzymes.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging its halogenated aniline and nitrile functionalities.
• Dye and Pigment Manufacturing: Serves as a starting material for producing specialized azo dyes and high-performance pigments.
• Material Science Research: Employed in the creation of novel polymers, liquid crystals, and organic electronic materials due to its rigid, substituted benzene core.
• Cross-Coupling Reactions: A valuable substrate in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination) for constructing complex biaryl and heteroaryl structures.

Basic Information

Product Name	4-Amino-3-Chloro-2-Methylbenzonitrile
CAS No.	573767-71-2
Molecular Formula	C8H7ClN2
Molecular Weight	166.61 g/mol
Synonyms	3-Chloro-4-amino-2-methylbenzonitrile; 2-Methyl-3-chloro-4-aminobenzonitrile; 4-Amino-3-chloro-o-tolunitrile; Benzonitrile, 4-amino-3-chloro-2-methyl-; 2-Methyl-4-amino-3-chlorobenzonitrile
EINECS	Contact for details

Quality Control

Our 4-Amino-3-Chloro-2-Methylbenzonitrile is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to verify identity and purity. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.