Description

(S)-4-(1-Hydroxymethyl-Propylamino)Benzonitrile is a chiral benzonitrile derivative of significant interest in advanced organic synthesis. This compound matters as a key chiral intermediate or building block for the development of enantiomerically pure pharmaceuticals and agrochemicals. It is primarily needed by research and development chemists, process development scientists, and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries who require high-purity, optically active intermediates for complex synthesis.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting neurological or cardiovascular pathways.
• Agrochemical Synthesis: Used in the research and production of enantiomerically pure herbicides, fungicides, or plant growth regulators where specific stereochemistry is required for bioactivity.
• Ligand and Catalyst Development: Acts as a precursor for chiral ligands or organocatalysts used in asymmetric synthesis to control stereoselectivity.
• Fine Chemical Research: Employed in academic and industrial R&D for exploring new synthetic methodologies and creating novel chemical entities with potential biological activity.
• Material Science Precursor: Potential use as a monomer or functionalizing agent in the synthesis of specialized polymers or advanced organic materials.

Basic Information

Product Name	(S)-4-(1-Hydroxymethyl-Propylamino)Benzonitrile
CAS No.	572923-29-6
Molecular Formula	C12H16N2O
Molecular Weight	204.27 g/mol
Synonyms	(S)-4-[(1-Hydroxymethyl-propyl)amino]benzonitrile; (S)-4-(1-Hydroxy-2-methyl-propylamino)benzonitrile; Benzonitrile, 4-[(1S)-1-(hydroxymethyl)propyl]amino]-; (S)-4-(α-Hydroxybutylamino)benzonitrile; (S)-4-(1-Hydroxybutyl-2-amino)benzonitrile; (S)-HMPAB; (S)-4-(1-Hydroxymethylpropylamino)benzonitrile
EINECS	Contact for details

Quality Control

Our (S)-4-(1-Hydroxymethyl-Propylamino)Benzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.