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(S)-1-{(S)-2-[2-(Diphenylphosphino)Phenyl]-Ferrocenyl}Ethyldiphenylphosphine CAS NO 565184-37-4
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CAS No.:565184-37-4
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
(S)-1-{(S)-2-[2-(Diphenylphosphino)Phenyl]-Ferrocenyl}Ethyldiphenylphosphine is a highly specialized chiral ferrocenyl diphosphine ligand, a cornerstone in advanced asymmetric catalysis. Its value lies in enabling exceptionally high enantioselectivity and catalytic efficiency in critical carbon-carbon and carbon-heteroatom bond-forming reactions. This compound is essential for research and process chemists in the pharmaceutical, agrochemical, and fine chemical industries who require precise stereochemical control for synthesizing chiral intermediates and active ingredients.
Application
- Asymmetric hydrogenation of prochiral olefins, ketones, and imines for pharmaceutical intermediate synthesis.
- Enantioselective cross-coupling reactions, including Suzuki-Miyaura and Negishi couplings.
- Catalyst ligand for asymmetric hydroformylation and hydroboration reactions.
- Key chiral inducer in the synthesis of complex natural products and agrochemicals.
- Research and development of novel catalytic systems in academic and industrial laboratories.
- Production of enantiomerically pure flavors, fragrances, and electronic chemicals.
Basic Information
| Product Name | (S)-1-{(S)-2-[2-(Diphenylphosphino)Phenyl]-Ferrocenyl}Ethyldiphenylphosphine |
| CAS No. | 565184-37-4 |
| Molecular Formula | C46H38FeP2 |
| Molecular Weight | 708.58 g/mol |
| Synonyms | (S,S)-JOSIPHOS SL-J009-1; (S)-1-[(S)-2-(2-Diphenylphosphinophenyl)ferrocenyl]ethyldiphenylphosphine; Josiphos SL-J009-1; (S)-1-[(S)-2-[2-(Diphenylphosphino)phenyl]ferrocenyl]ethyldiphenylphosphine; (S,S)-1-[(R)-2-[2-(Diphenylphosphino)phenyl]ferrocenyl]ethyldiphenylphosphine; (1S)-1-[(SP)-2-[2-(Diphenylphosphanyl)phenyl]ferrocenyl]ethyldiphenylphosphane; Chiral Ferrocenyl Diphosphine Ligand J009-1 |
| EINECS | Contact for details |
Quality Control
Every batch of our chiral ligands undergoes rigorous analytical testing to ensure identity, purity, and enantiomeric excess meet the stringent requirements of catalytic applications. Our quality management system supports production under inert atmosphere to prevent oxidation. A comprehensive Certificate of Analysis (COA) detailing results from NMR, HPLC, and chiral analysis is provided with each shipment.
Storage
Preserve in a tightly closed container, protected from light. For long-term stability, store under an inert atmosphere (argon or nitrogen) at 2-8°C. The material is easily oxidized (store under inert atmosphere) and light-sensitive (store away from light). Allow the sealed container to reach ambient temperature before opening to prevent moisture condensation.
Specification
| Item | Specification |
|---|---|
| Appearance | Orange to red crystalline powder |
| Identification (IR) | Conforms to structure |
| Purity (HPLC) | ≥ 97.0% |
| Enantiomeric Excess (Chiral HPLC) | ≥ 99.0% ee |
| Solubility | Soluble in common organic solvents (THF, Toluene, DCM) |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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